Ethylamino-phenyl-acetic acid → (Ethyl-methoxycarbonyl-amino)-phenyl-acetic acid
Reaction equation
F[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH:8]([NH:12][C:13]([O:15][CH3:16])=[O:14])[C:9]([OH:11])=[O:10].[CH2:17](NC(C1C=CC=CC=1)C(O)=O)[CH3:18]>>[CH2:17]([N:12]([CH:8]([C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][CH:2]=1)[C:9]([OH:11])=[O:10])[C:13]([O:15][CH3:16])=[O:14])[CH3:18]Participants
3
Procedure
(Ethyl-methoxycarbonyl-amino)-phenyl-acetic acid was prepared using the procedure used to prepare (2-Fluoro-phenyl)-methoxycarbonylamino-acetic acid using Ethylamino-phenyl-acetic acid. LCMS-ESI+: calc'd for C12H15NO4: 237.10 (M+); Found: 238.03 (M+H+).
Sources & evidence
- ORD record
- ord-a21b9619a83d415586be53b16c8e5def
- Source dataset
- uspto-grants-2015_10
- Patent number
- US09156823B2
Reaction notes
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