(alphaR)-alpha-((Methoxycarbonyl)amino)benzeneacetic acid → HCID 86708759, compound

Participants

Role	Name	HCID	Charge
Reactant	(alphaR)-alpha-((Methoxycarbonyl)amino)benzeneacetic acid	HCID 10910775	—
Reactant	methyl (S)-1-((S)-2-(5-(8-(2-((5)-1-((R)-2-methoxycarbonylamino-2-phenylacetyl)-pyrrolidin-2-yl)-1H-imidazol-5-yl)-6H-dibenzo[c,h]chromen-2-yl)-1H-imidazol-2-yl)pyrrolidin-1-yl)-3-methyl-1-oxobutan-2-ylcarbamate	HCID 86708758	—
Product	HCID 86708759	HCID 86708759	—

Reaction Steps

This compound was made in an analogous manner to methyl (S)-1-((S)-2-(5-(8-(2-((S)-1-((R)-2-methoxycarbonylamino-2-phenylacetyl)-pyrrolidin-2-yl)-1H-imidazol-5-yl)-6H-dibenzo[c,h]chromen-2-yl)-1H-imidazol-2-yl)pyrrolidin-1-yl)-3-methyl-1-oxobutan-2-ylcarbamate, substituting (S)-2-(methoxycarbonylamino)-2-(tetrahydro-2H-pyran-4-yl)acetic acid for (R)-2-(methoxycarbonylamino)-2-phenylacetic acid in the second amide coupling. LCMS-ESI+: calculated for C47H54N8O8: 858.98; observed [M+1]+: 860.02.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US09156823B2
Source dataset	uspto-grants-2015_10
ORD ID	ord-bd03c767e26d4e5e8f920be36b290691
Source note	uspto-grants-2015_10