Tert-butyl 2,2,2-trichloroethanimidate → Tert-butyl 2-acetoxy-2-(3-bromophenyl)acetate

Participants

Reaction Steps

To a solution of compound 2 (500 mg, 1.83 mmol) in toluene (2.5 mL) was added t-butyl-trichloroacetimidate (0.33 mL). The reaction was stirred at room temperature for 5 hours. The solid precipitate was filtered off and washed with toluene. The filtrate was concentrated in vacuo to provide compound 3 which was used in the next reaction without further purification.

Provenance & Evidence