HRID1751812

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID13203

2-Chlorocyclohexanone

C6H9ClO

HCID783156

1-benzylpiperidine-4-carboxamide

C13H18N2O

PRODUCTS

产物

反应SMILES：c1ccc(CN2CCC(c3nc4c(o3)CCCC4)CC2)cc1

HCID58080363

未命名化合物

收率 70.9%

CONDITIONS

反应条件

温度: 160 °C

PROCEDURE

实验过程

A mixture of 2.43 g 2-chlorocyclohexanone and 1 g 1-benzylpiperidine-4-carboxylic acid amide (WO2005/61483) is heated to 160° C. in the microwave until there is no further reaction. The product is purified by chromatography. 963 mg of the product are obtained. Analytical HPLC-MS (method B): RT=1.28 min.

WORKUP

后处理

customno further reaction
customThe product is purified by chromatography