HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrrole → 1-Phenylpyrrole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrrole | HCID 8027 | — |
| Reactant | Iodobenzene | HCID 11575 | — |
| Product | 1-Phenylpyrrole | HCID 12480 | — |
Reaction Steps
Following General Procedure A (90° C., 30 hours), 1H-pyrrole (104 μL, 1.5 mmol) is coupled with iodo-benzene (112 μL, 1.0 mmol). The crude brown oil is purified by flash chromatography on silica gel (eluent: hexanes) to provide 130 mg (91% isolated yield) of the desired product as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09162953B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-0e590947af0b4147be9d3f1bc421548d |
| Source note | uspto-grants-2015_10 |