HuagongsheHuagongshe Chemistry Print Report · For research reference only
Indole → 1-Phenyl-1H-indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Indole | HCID 798 | — |
| Reactant | Iodobenzene | HCID 11575 | — |
| Product | 1-Phenyl-1H-indole | HCID 182029 | — |
Reaction Steps
Following General Procedure A (90° C., 30 hours), 1H-indole (176 mg, 1.5 mmol) is coupled with iodo-benzene (112 μL, 1.0 mmol). The crude brown oil is purified by flash chromatography on silica gel (eluent: hexanes) to provide 180 mg (93% isolated yield) of the desired product as a light green oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09162953B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-4afd82be9e7648e5a8dd98efbb7a1871 |
| Source note | uspto-grants-2015_10 |