HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen iodide → 4-Iodo-6-(2,3-difluoro-4-methoxyphenyl)pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen iodide | HCID 24841 | — |
| Reactant | 4,6-Dichloropyrimidine | HCID 70943 | — |
| Reactant | 2,3-Difluoro-4-methoxybenzeneboronic acid | HCID 25067272 | — |
| Product | 4-Iodo-6-(2,3-difluoro-4-methoxyphenyl)pyrimidine | HCID 51355000 | — |
Reaction Steps
The compound was prepared according to Example 1 using 2,3-difluoro-4-methoxyphenylboronic acid and 4,6-dichloropyrimidine. The resultant chloro compound was converted to iodo with hydroiodic acid as described in the general procedure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09162987B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-645c0b9f63b24d948f074bc3641f0819 |
| Source note | uspto-grants-2015_10 |