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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1752004Generated: October 27, 2026

Hydrogen iodide → 4-Iodo-6-(4-ethoxyphenyl)pyrimidine

https://huagongshe.com/reaction/1752004

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrogen iodideHCID 24841—
Reactant4,6-DichloropyrimidineHCID 70943—
Reactant(4-Ethoxy-3-fluorophenyl)boronic acidHCID 2782821—
Product4-Iodo-6-(4-ethoxyphenyl)pyrimidineHCID 51355571—

Reaction Steps

The compound was prepared according to Example 1 using 3-fluoro-4-ethoxyphenylboronic acid and 4,6-dichloropyrimidine. The resultant chloro compound was converted to iodo with hydroiodic acid as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09162987B2
Source datasetuspto-grants-2015_10
ORD IDord-06a354a8cc4c4b6b8452ec38e1ce6158
Source noteuspto-grants-2015_10