HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Bromo-2-methylpropane → HCID 57762509, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Bromo-2-methylpropane | HCID 6555 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | N-(4-iodophenyl)pyrimidin-2-amine | HCID 57762548 | — |
| Product | HCID 57762509 | HCID 57762509 | 93.6% |
Reaction Steps
In the same manner as in Reference Example 13, N-(4-iodophenyl)pyrimidin-2-amine (150 mg) and isobutyl bromide (83 mg) were reacted in the presence of sodium hydride to obtain N-(4-iodophenyl)-N-isobutylpyrimidin-2-amine (167 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09162988B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-82585c0ed682407fa44837634a381cb9 |
| Source note | uspto-grants-2015_10 |