HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 57762590, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 4-(Bromomethyl)pyridine hbr | HCID 12752219 | — |
| Reactant | N-(4-iodophenyl)pyrimidin-2-amine | HCID 57762548 | — |
| Product | HCID 57762590 | HCID 57762590 | 23.7% |
Reaction Steps
In the same manner as in Reference Example 22, N-(4-iodophenyl)pyrimidin-2-amine (300 mg) and 4-bromomethylpyridine hydrobromide (307 mg) were reacted in the presence of sodium hydride to obtain N-(4-iodophenyl)-N-((pyridin-4-yl)methyl)pyrimidin-2-amine (93 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09162988B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-59b2797e751443c7948467a11695582d |
| Source note | uspto-grants-2015_10 |