HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 57762511, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 2-(Bromomethyl)pyridine hydrobromide | HCID 2734720 | — |
| Reactant | N-(4-iodophenyl)pyrimidin-2-amine | HCID 57762548 | — |
| Product | HCID 57762511 | HCID 57762511 | 71.9% |
Reaction Steps
In the same manner as in Reference Example 22, N-(4-iodophenyl)pyrimidin-2-amine (300 mg) and 2-bromomethylpyridine hydrobromide (307 mg) were reacted in the presence of sodium hydride to obtain N-(4-iodophenyl)-N-((pyridin-2-yl)methyl)pyrimidin-2-amine (282 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09162988B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-1928a753f4b644daaac412bed9797cb7 |
| Source note | uspto-grants-2015_10 |