HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-chloro-2-N,4-N-dipropyl-1,3,5-triazine-2,4-diamine → O-benzyl-N-(4,6-bis-propylamino-[1,3,5]triazin-2-yl)-N-methyl-hydroxylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-chloro-2-N,4-N-dipropyl-1,3,5-triazine-2,4-diamine | HCID 18304 | — |
| Reactant | (Benzyloxy)(methyl)amine | HCID 13417387 | — |
| Product | O-benzyl-N-(4,6-bis-propylamino-[1,3,5]triazin-2-yl)-N-methyl-hydroxylamine | HCID 57377806 | 29% |
Reaction Steps
2-Chloro-N-(4,6-bis-(n-propylamino)-[1,3,5]triazine (XXXIV) and O-benzyl-N-methyl-hydroxylamine (LII) were reacted as described in Example 13 to yield O-benzyl-N-(4,6-bis-n-propylamino-[1,3,5]triazin-2-yl)-N-methyl-hydroxylamine (LIII) (29% yield). 200 MHz 1H NMR (DMSO-d6, ppm) 7.52-7.28 (5H, m), 7.07-6.67 (2H, m), 4.93 (2H, s), 3.26-3.03 (7H, m), 1.58-1.39 (4H, m), 0.85 (6H, t, J=7.2 Hz). ESI-MS (m/z): 331 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09162992B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-a272c6ea3e5643fbbba67f742accc28d |
| Source note | uspto-grants-2015_10 |