6-chloro-2-N,4-N-dipropyl-1,3,5-triazine-2,4-diamine → HCID 57377914, compound

HRID 1752135Notes

Reaction equation

HRID 1752135 reaction equation
Cl[C:2]1[N:7]=[C:6]([NH:8][CH2:9][CH2:10][CH3:11])[N:5]=[C:4]([NH:12][CH2:13][CH2:14][CH3:15])[N:3]=1.Cl.[CH2:17]([O:21][NH:22][CH3:23])[CH:18]([CH3:20])[CH3:19]>>[CH2:13]([NH:12][C:4]1[N:5]=[C:6]([NH:8][CH2:9][CH2:10][CH3:11])[N:7]=[C:2]([N:22]([CH3:23])[O:21][CH2:17][CH:18]([CH3:20])[CH3:19])[N:3]=1)[CH2:14][CH3:15]

Participants

3

Reactant 2

HCID 183046-chloro-2-N,4-N-dipropyl-1,3,5-triazine-2,4-diamineHCID 86665985HCID 86665985, compound

Product 1

HCID 57377914HCID 57377914, compoundYield 82%

Procedure

2-Chloro-N-(4,6-bis-(n-propylamino)-[1,3,5]triazine (XXXIV) was reacted with O-isobutyl-N-methyl-hydroxylamine hydrochloride as described in Example 13, affording LXXXII in 82% yield. ESI-MS (m/z) 297 [M+H]+.

Workup

  1. customaffording LXXXII in 82% yield

Sources & evidence

ORD record
ord-206704d3bcab4541953bcdf1f63a6761
Source dataset
uspto-grants-2015_10
Patent number
US09162992B2

Reaction notes

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