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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1752287Generated: October 28, 2026

Hydrochloric Acid → HCID 58171518, compound

https://huagongshe.com/reaction/1752287

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 69809720HCID 69809720—
SolventDichloromethaneHCID 6344—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 58171518HCID 58171518165.8%

Reaction Steps

tert-Butyl 3-(1-methyl-1H-benzo[d]imidazol-2-yl)pyrrolidine-1-carboxylate (93 mg) was dissolved in CH2Cl2 (3 mL) and 4 M HCl in dioxane (1 mL) was added. The mixture was stirred at rt for 3 h and concentrated to leave 1-methyl-2-(pyrrolidin-3-yl)-1H-benzo[d]imidazole (103 mg) as a red solid. LC-MS Method 1 tR=0.40 min, m/z=202.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09163012B2
Source datasetuspto-grants-2015_10
ORD IDord-77289f9253e14ec7812543bfad0cc684
Source noteuspto-grants-2015_10