Triethylamine → HCID 58171552, compound

Participants

Reaction Steps

To a solution of 2-(1-benzyl-pyrrolidin-3-yl)-5-methoxy-pyrimidine (100 mg, 0.37 mmol) and Et3N (37.6 mg, 0.37 mmol) in CH2Cl2 (2 mL) was added 1-chloroethyl carbonochloridate (63.8 mg, 0.45 mmol) dropwise at 0° C. The mixture was stirred at rt for 2 h. The reaction mixture was concentrated to afford crude 5-methoxy-2-(pyrrolidin-3-yl)pyrimidine (100 mg), which was used for next step without purification.

Provenance & Evidence