HuagongsheHuagongshe Chemistry Print Report · For research reference only
1H-Pyrazole-4-boronic acid → 5-Methyl-7-(1H-pyrazol-4-yl)-2-(2-quinolin-2-yl-ethyl)-3,5-dihydro-2H-pyrrolo[3,4-c]pyridine-1,6-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1H-Pyrazole-4-boronic acid | HCID 17750278 | — |
| Reactant | 7-Chloro-5-methyl-2-(2-(quinolin-2-YL)ethyl)-2,3-dihydro-1H-pyrrolo[3,4-C]pyridine-1,6(5H)-dione | HCID 73424728 | — |
| Product | 5-Methyl-7-(1H-pyrazol-4-yl)-2-(2-quinolin-2-yl-ethyl)-3,5-dihydro-2H-pyrrolo[3,4-c]pyridine-1,6-dione | HCID 86296473 | — |
Reaction Steps
The title compound was prepared in analogy to the process of Example 13 starting from 7-chloro-5-methyl-2-(2-quinolin-2-yl-ethyl)-3,5-dihydro-2H-pyrrolo[3,4-c]pyridine-1,6-dione (see Example c4)) and 1H-pyrazol-4-ylboronic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09163019B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-f4d24008f3944406a3e69f8d7d48f3ce |
| Source note | uspto-grants-2015_10 |