HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopentylamine → HCID 67249098, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopentylamine | HCID 2906 | — |
| Reactant | Ethyl 4-chloro-8-ethylquinoline-3-carboxylate | HCID 14710177 | — |
| Product | HCID 67249098 | HCID 67249098 | — |
Reaction Steps
4-Chloro-8-ethyl-quinoline-3-carboxylic acid ethyl ester (250 mg, 0.95 mmol) was treated with cyclopentylamine following general procedure B to afford 4-cyclopentylamino-8-ethyl-quinoline-3-carboxylic acid ethyl ester (250 mg). Thus obtained amino-ester was hydrolyzed to the corresponding acid in quantitative yield using general procedure D and then transformed into the corresponding ethylamide (180 mg) following general procedure E.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09163022B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-1b862e26a4fd4975bc75daf031ffd69f |
| Source note | uspto-grants-2015_10 |