HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Isocyanatothiophene → 1-Cyclopentyl-7-methoxy-3-thiophen-3-yl-1H-pyrimido[5,4-c]quinoline-2,4-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Isocyanatothiophene | HCID 2776380 | — |
| Reactant | 4-Cyclopentylamino-8-methoxy-quinoline-3-carboxylic acid ethyl ester | HCID 67249718 | — |
| Product | 1-Cyclopentyl-7-methoxy-3-thiophen-3-yl-1H-pyrimido[5,4-c]quinoline-2,4-dione | HCID 58329451 | — |
Reaction Steps
1-Cyclopentyl-7-methoxy-3-thiophen-3-yl-1H-pyrimido[5,4-c]quinoline-2,4-dione (21 mg) was prepared from 4-cyclopentylamino-8-methoxy-quinoline-3-carboxylic acid ethyl ester (0.1. mmol) and 3-isocyanato-thiophene (0.5 mmol) following general procedure C. LCMS: m/z 394 [M+1]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09163022B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-146abfeb23994b81b5e9051cba7dcacc |
| Source note | uspto-grants-2015_10 |