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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1752726Generated: October 28, 2026

3-Isocyanato-5-methyl-2-(trifluoromethyl)furan → HCID 58329440, compound

https://huagongshe.com/reaction/1752726

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Isocyanato-5-methyl-2-(trifluoromethyl)furanHCID 2779896—
Reactant4-Cyclopentylamino-8-methoxy-quinoline-3-carboxylic acid ethyl esterHCID 67249718—
ProductHCID 58329440HCID 5832944054.4%

Reaction Steps

1-Cyclopentyl-7-methoxy-3-(5-methyl-2-trifluoromethyl-furan-3-yl)-1H-pyrimido[5,4-c]quinoline-2,4-dione (25 mg) was prepared from 4-cyclopentylamino-8-methoxy-quinoline-3-carboxylic acid ethyl ester (0.1 mmol) and 3-isocyanato-5-methyl-2-trifluoromethyl-furan (0.5 mmol) following general procedure C. LCMS: m/z 460 [M+1]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09163022B2
Source datasetuspto-grants-2015_10
ORD IDord-698f2584eeda4571aadb8429b413c54c
Source noteuspto-grants-2015_10