HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2-Dibromoethane → HCID 86719316, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2-Dibromoethane | HCID 7839 | — |
| Reactant | 3,4-Difluorophenol | HCID 75927 | — |
| Reactant | HCID 22471323 | HCID 22471323 | — |
| Reactant | 1373822-50-4 | HCID 75360926 | — |
| Reactant | HCID 178426287 | HCID 178426287 | — |
| Product | HCID 22471323 | HCID 22471323 | — |
| Product | HCID 86719316 | HCID 86719316 | 36% |
Reaction Steps
The title compound was prepared according to the experimentals described for Example 1 above from 5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-thiol and 3,4-difluorophenoxy-ethylbromide in 36% yield. The reagent 3,4-difluorophenoxy-ethylbromide was prepared by a similar procedure for the synthesis of 4-chloro-3-fluorophenoxy-ethylbromide in Example 4 above from 3,4-difluorophenol and 1,2-dibromoethane. EM (calc.): 336.1; MS (ESI) m/e: 337.1 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09163027B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-17a475d15834408c90428fe488f98e5b |
| Source note | uspto-grants-2015_10 |