Cyclopentanepropanol → 2-(3-Cyclopentylpropoxy)-5,7-dimethyl-[1,2,4]-triazolo[1,5-a]pyrimidine

HRID 1752794Notes

Reaction equation

HRID 1752794 reaction equation
CS([C:5]1[N:15]=[C:8]2[N:9]=[C:10]([CH3:14])[CH:11]=[C:12]([CH3:13])[N:7]2[N:6]=1)(=O)=O.[CH:16]1([CH2:21][CH2:22][CH2:23][OH:24])[CH2:20][CH2:19][CH2:18][CH2:17]1>>[CH:16]1([CH2:21][CH2:22][CH2:23][O:24][C:5]2[N:15]=[C:8]3[N:9]=[C:10]([CH3:14])[CH:11]=[C:12]([CH3:13])[N:7]3[N:6]=2)[CH2:20][CH2:19][CH2:18][CH2:17]1

Participants

3

Reactant 2

HCID 69842CyclopentanepropanolHCID 713561592-(Methanesulfonyl)-5,7-dimethyl[1,2,4]triazolo[1,5-a]pyrimidine

Product 1

HCID 867193182-(3-Cyclopentylpropoxy)-5,7-dimethyl-[1,2,4]-triazolo[1,5-a]pyrimidineYield 52%

Procedure

The title compound was prepared according to the experimentals described for Example 11 above from 2-methanesulfonyl-5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidine and 3-cyclopentyl-1-propanol in 52% yield. EM (calc.): 274.2; MS (ESI) m/e: 275.3 (M+H)+.

Sources & evidence

ORD record
ord-e202c9b8102d4803828245858963df2b
Source dataset
uspto-grants-2015_10
Patent number
US09163027B2

Reaction notes

Loading…