1,1,3,3-Tetraethoxypropane → HCID 47134898, compound

HRID 1752815Notes

Reaction equation

HRID 1752815 reaction equation
[Cl:1][C:2]1[CH:17]=[CH:16][C:5]([O:6][CH2:7][CH2:8][S:9][C:10]2[N:14]=[C:13]([NH2:15])[NH:12][N:11]=2)=[CH:4][CH:3]=1.CCO[CH:21](OCC)[CH2:22][CH:23](OCC)OCC>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([O:6][CH2:7][CH2:8][S:9][C:10]2[N:14]=[C:13]3[N:15]=[CH:21][CH:22]=[CH:23][N:12]3[N:11]=2)=[CH:16][CH:17]=1

Participants

3

Reactant 2

HCID 671471,1,3,3-TetraethoxypropaneHCID 1648919HCID 1648919, compound

Product 1

HCID 47134898HCID 47134898, compoundYield 42%

Procedure

The title compound was prepared according to the experimentals described for Example 23 above from 3-{[2-(4-chlorophenoxy)ethyl]sulfanyl}-1H-1,2,4-triazol-5-amine and malonaldehyde bis(diethyl acetal) in 42% yield; EM (calc.): 306.0; MS (ESI) m/e: 307.0 (M+H)+. 1H NMR (DMSO-d6, 400 MHz) δ ppm: 9.33 (dd, 1H), 8.81 (dd, 1H), 7.31 (m, 3H), 7.02 (dt, 2H), 4.33 (t, 2H), 3.62 (t, 2H).

Sources & evidence

ORD record
ord-484e5750d00a4da499593beb2f0e6c26
Source dataset
uspto-grants-2015_10
Patent number
US09163027B2

Reaction notes

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