N-bromobutanimide → HCID 86607691, compound

HRID 1752869Notes

Reaction equation

HRID 1752869 reaction equation
[CH:1]([C:3]1[CH:4]=[C:5]([CH2:10][C:11]#[N:12])[CH:6]=[CH:7][C:8]=1[OH:9])=[O:2].[Br:13]N1C(=O)CCC1=O>>[Br:13][C:7]1[CH:6]=[C:5]([CH2:10][C:11]#[N:12])[CH:4]=[C:3]([CH:1]=[O:2])[C:8]=1[OH:9]

Participants

3

Reactant 2

HCID 67184N-bromobutanimideHCID 866076902-(3-Formyl-4-hydroxyphenyl)acetonitrile

Product 1

HCID 86607691HCID 86607691, compoundYield 80.6%

Procedure

Proceeding as in Reference 9, but substituting 3-formyl-4-hydroxyphenylacetonitrile (1 g, 6.2 mmol) and N-bromosuccinimide (1.7 g, 9.3 mmol), gave 3-bromo-5-formyl-4-hydroxyphenylacetonitrile (1.2 g).

Sources & evidence

ORD record
ord-cce7410ae6824ad089069067128d5213
Source dataset
uspto-grants-2015_10
Patent number
US09162986B2

Reaction notes

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