HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(Chloromethoxy)-2-methoxyethane → Methyl 3-bromo-5-formyl-4-(2-methoxyethoxymethoxy)-benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(Chloromethoxy)-2-methoxyethane | HCID 77590 | — |
| Reactant | Methyl 3-bromo-5-formyl-4-hydroxybenzoate | HCID 71711084 | — |
| Product | Methyl 3-bromo-5-formyl-4-(2-methoxyethoxymethoxy)-benzoate | HCID 86607700 | 96% |
Reaction Steps
Proceeding as in Reference 12, but substituting methyl 3-bromo-5-formyl-4-hydroxybenzoate (12.6 g, 48.6 mmol, 1.0 eq.) and methoxyethoxymethyl chloride (6.8 mL, 7.26 g, 58.3 mmol, 1.2 eq.), gave methyl 3-bromo-5-formyl-4-(2-methoxyethoxymethoxy)-benzoate (16.2 g) as a colorless oil which solidified upon standing.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09162986B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-d809db375e2c43d28928f0fb88893fba |
| Source note | uspto-grants-2015_10 |