Toluene → HCID 86607702, compound

HRID 1752890Notes

Reaction equation

HRID 1752890 reaction equation
Br[C:2]1[CH:3]=[C:4]([CH2:15][C:16]([O-:18])=[O:17])[CH:5]=[CH:6][C:7]=1[O:8][CH2:9][O:10][CH2:11][CH2:12][O:13][CH3:14].[CH3:19][O:20][CH2:21][CH2:22][O:23][CH2:24][O:25][C:26]1[C:33](B2OC(C)(C)C(C)(C)O2)=[CH:32][CH:31]=[CH:30][C:27]=1[CH:28]=[O:29].[C:43]1(C)C=CC=CC=1>>[CH:28]([C:27]1[C:26]([O:25][CH2:24][O:23][CH2:22][CH2:21][O:20][CH3:19])=[C:33]([C:2]2[C:7]([O:8][CH2:9][O:10][CH2:11][CH2:12][O:13][CH3:14])=[CH:6][CH:5]=[C:4]([CH2:15][C:16]([O:18][CH3:43])=[O:17])[CH:3]=2)[CH:32]=[CH:31][CH:30]=1)=[O:29]

Participants

4

Reactant 3

HCID 1140TolueneHCID 86607703HCID 86607703, compoundHCID 86607704HCID 86607704, compound

Product 1

HCID 86607702HCID 86607702, compound

Procedure

Proceeding as in Reference 19, but substituting 3-bromo-4-(2-methoxyethoxymethoxy)phenylacetate (2.43 g, 7.28 mmol) and 2-(2-methoxyethoxymethoxy)-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)benzaldehyde in toluene (7.28 mmol, 0.1 M, 73 mL), gave methyl [3′-formyl-6,2′-bis(2-methoxyethoxymethoxy)biphenyl-3-yl]acetate (2.42 g).

Sources & evidence

ORD record
ord-7750e53a4c98451b9954bdc1f27f50f8
Source dataset
uspto-grants-2015_10
Patent number
US09162986B2

Reaction notes

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