HCID 86607696, compound → HCID 86607717, compound

HRID 1752904Notes

Reaction equation

HRID 1752904 reaction equation
Br[C:2]1[CH:3]=[C:4]([CH:14]=[CH:15][C:16]=1[O:17][CH2:18][O:19][CH2:20][CH2:21][O:22][CH3:23])[CH2:5][NH:6][C:7](=[O:13])[O:8][C:9]([CH3:12])([CH3:11])[CH3:10].[CH3:24][O:25][CH2:26][CH2:27][O:28][CH2:29][O:30][C:31]1[C:38](B2OC(C)(C)C(C)(C)O2)=[CH:37][CH:36]=[CH:35][C:32]=1[CH:33]=[O:34]>>[CH:33]([C:32]1[C:31]([O:30][CH2:29][O:28][CH2:27][CH2:26][O:25][CH3:24])=[C:38]([C:2]2[C:16]([O:17][CH2:18][O:19][CH2:20][CH2:21][O:22][CH3:23])=[CH:15][CH:14]=[C:4]([CH2:5][NH:6][C:7](=[O:13])[O:8][C:9]([CH3:12])([CH3:11])[CH3:10])[CH:3]=2)[CH:37]=[CH:36][CH:35]=1)=[O:34]

Participants

3

Reactant 2

HCID 86607696HCID 86607696, compoundHCID 86607704HCID 86607704, compound

Product 1

HCID 86607717HCID 86607717, compound

Procedure

Proceeding as in Reference 19, but substituting tert-butyl [3-bromo-4-(2-methoxyethoxymethoxy)-benzyl]carbamate (2.3 g, 5.9 mmol) and 2-(2-methoxyethoxymethoxy)-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzaldehyde (60 mL, 0.1 M in toluene), gave tert-butyl [3′-formyl-6,2′-bis(2-methoxyethoxymethoxy)biphenyl-3-ylmethyl]carbamate (2.96 g).

Sources & evidence

ORD record
ord-409dac0b2c5e4d5184ce0ee8a030f695
Source dataset
uspto-grants-2015_10
Patent number
US09162986B2

Reaction notes

Loading…