Benzoyl chloride → N-benzoyl-3'-amino-5-formyl-6-methoxy-biphenyl-3-sulfonamide
Reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([C:8]2[C:13]([O:14][CH3:15])=[C:12]([CH:16]=[O:17])[CH:11]=[C:10]([S:18]([NH2:21])(=[O:20])=[O:19])[CH:9]=2)[CH:5]=[CH:6][CH:7]=1.[C:22](Cl)(=[O:29])[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1>>[C:22]([NH:21][S:18]([C:10]1[CH:9]=[C:8]([C:4]2[CH:5]=[CH:6][CH:7]=[C:2]([NH2:1])[CH:3]=2)[C:13]([O:14][CH3:15])=[C:12]([CH:16]=[O:17])[CH:11]=1)(=[O:19])=[O:20])(=[O:29])[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1Participants
3
Procedure
Proceeding as in Reference 21, but substituting 3′-amino-5-formyl-6-methoxy-biphenyl-3-sulfonamide and benzoyl chloride, gave N-benzoyl-3′-amino-5-formyl-6-methoxy-biphenyl-3-sulfonamide.
Sources & evidence
- ORD record
- ord-119574419d6543e38cf786c5caec8e4f
- Source dataset
- uspto-grants-2015_10
- Patent number
- US09162986B2
Reaction notes
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