3'-Amino-5-formyl-6-methoxy-biphenyl-3-sulfonamide → 3'-amino-5-formyl-6-methoxy-N-(3-piperidin-3-ylpropanoyl)-biphenyl-3-sulfonamide

HRID 1752924Notes

Reaction equation

HRID 1752924 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([C:8]2[C:13]([O:14][CH3:15])=[C:12]([CH:16]=[O:17])[CH:11]=[C:10]([S:18]([NH2:21])(=[O:20])=[O:19])[CH:9]=2)[CH:5]=[CH:6][CH:7]=1.[NH:22]1[CH2:27][CH2:26][CH2:25][CH:24]([CH2:28][CH2:29][C:30](Cl)=[O:31])[CH2:23]1>>[NH2:1][C:2]1[CH:3]=[C:4]([C:8]2[C:13]([O:14][CH3:15])=[C:12]([CH:16]=[O:17])[CH:11]=[C:10]([S:18]([NH:21][C:30](=[O:31])[CH2:29][CH2:28][CH:24]3[CH2:25][CH2:26][CH2:27][NH:22][CH2:23]3)(=[O:19])=[O:20])[CH:9]=2)[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 866077123'-Amino-5-formyl-6-methoxy-biphenyl-3-sulfonamideHCID 866077353-Piperidin-3-ylpropanoyl chloride

Product 1

HCID 866077343'-amino-5-formyl-6-methoxy-N-(3-piperidin-3-ylpropanoyl)-biphenyl-3-sulfonamide

Procedure

Proceeding as in Reference 21, but substituting 3′-amino-5-formyl-6-methoxy-biphenyl-3-sulfonamide and 3-piperidin-3-ylpropanoyl chloride, gave 3′-amino-5-formyl-6-methoxy-N-(3-piperidin-3-ylpropanoyl)-biphenyl-3-sulfonamide.

Sources & evidence

ORD record
ord-9a8d70b4c11f4091aad870eee69ffc33
Source dataset
uspto-grants-2015_10
Patent number
US09162986B2

Reaction notes

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