HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4-Diaminobenzimidamide hydrochloride → HCID 178479303, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4-Diaminobenzimidamide hydrochloride | HCID 22125532 | — |
| Reactant | Methyl 3'-tert-butylsulfamoyl-5-formyl-6-(2-methoxyethoxymethoxy)-biphenyl-3-carboxylate | HCID 86607699 | — |
| Product | HCID 178479303 | HCID 178479303 | 39% |
Reaction Steps
Proceeding as in Reference 23, but substituting 3′-tert-butylsulfamoyl-5-formyl-6-(2-methoxyethoxymethoxy)-biphenyl-3-carboxylic acid methyl ester (1.64 g, 3.42 mmol, 1.0 eq.) and 3,4-diamino-benzamidine hydrochloride (638 mg, 3.42 mmol, 1.0 eq.), gave 5-(5-carbamimidoyl-1H-benzoimidazol-2-yl)-6-hydroxy-3′-sulfamoyl-biphenyl-3-carboxylic acid hydrochloride (650 mg) as a brown solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09162986B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-295373cdf45e447682fa5a3899ee0e60 |
| Source note | uspto-grants-2015_10 |