5-Bromo-2-(5-methyl-1,3,4-oxadiazol-2-yl)pyridine → HCID 67075374, compound

HRID 1752950Notes

Reaction equation

HRID 1752950 reaction equation
C[Sn](C)(C)[C:3]1([F:18])[CH:8]=[CH:7][C:6]([N:9]2[CH2:13][C@H:12]([CH2:14][OH:15])[O:11][C:10]2=[O:16])=[CH:5][CH:4]1[F:17].[CH3:21][C:22]1[O:23][C:24]([C:27]2[CH:32]=[CH:31][C:30](Br)=[CH:29][N:28]=2)=[N:25][N:26]=1>>[CH3:21][C:22]1[O:23][C:24]([C:27]2[CH:32]=[CH:31][C:30]([C:3]3([F:18])[CH:8]=[CH:7][C:6]([N:9]4[CH2:13][C@H:12]([CH2:14][OH:15])[O:11][C:10]4=[O:16])=[CH:5][CH:4]3[F:17])=[CH:29][N:28]=2)=[N:25][N:26]=1

Participants

3

Reactant 2

HCID 234386435-Bromo-2-(5-methyl-1,3,4-oxadiazol-2-yl)pyridineHCID 68820223HCID 68820223, compound

Product 1

HCID 67075374HCID 67075374, compound

Procedure

The same procedure as in Example 1 was conducted by using (R)-3-(4-trimethylstannyl-3,4-difluorophenyl)-2-oxo-5-oxazolidinylmethanol and 2-(2-methyl-[1,3,4]oxadiazol-5-yl)-5-bromopyridine as a starting material, to prepare the title compound.

Sources & evidence

ORD record
ord-81edb186239742ed8ba63a2656407d84
Source dataset
uspto-grants-2015_10
Patent number
US09163043B2

Reaction notes

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