HCID 67074691, compound → HCID 86613475, compound

HRID 1752956Notes

Reaction equation

HRID 1752956 reaction equation
[N:1]1[N:2]([C:6]2[CH:11]=[CH:10][C:9](Br)=[CH:8][N:7]=2)[N:3]=[CH:4][CH:5]=1.C[Sn](C)(C)[C:15]1[CH:20]=[CH:19][C:18]([N:21]2[CH2:25][C@H:24]([CH2:26][C:27](=[O:31])[C:28]([NH2:30])=[O:29])[O:23][CH2:22]2)=[CH:17][C:16]=1[F:32]>>[N:1]1[N:2]([C:6]2[CH:11]=[CH:10][C:9]([C:15]3[CH:20]=[CH:19][C:18]([N:21]4[CH2:25][C@H:24]([CH2:26][C:27](=[O:31])[C:28]([NH2:30])=[O:29])[O:23][CH2:22]4)=[CH:17][C:16]=3[F:32])=[CH:8][N:7]=2)[N:3]=[CH:4][CH:5]=1

Participants

3

Reactant 2

HCID 67074691HCID 67074691, compoundHCID 86613473HCID 86613473, compound

Product 1

HCID 86613475HCID 86613475, compound

Procedure

The same procedure as in Example 1 was conducted, except for adding 2-([1,2,3]triazol-2-yl)-5-bromopyridine and using (S)-3-(4-trimethylstannyl-3-fluorophenyl)-2-oxo-5-oxazolidinylmethyl acetamide as a starting material, to obtain the title compound.

Sources & evidence

ORD record
ord-124b8d3b6c54442da680a40389d64abb
Source dataset
uspto-grants-2015_10
Patent number
US09163043B2

Reaction notes

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