HCID 57471690, compound → HCID 86613477, compound

HRID 1752958Notes

Reaction equation

HRID 1752958 reaction equation
[C:1]([CH2:3][C:4]1[N:5]=[C:6]([C:9]2[CH:14]=[CH:13][C:12](Br)=[CH:11][CH:10]=2)[S:7][CH:8]=1)#[N:2].C[Sn](C)(C)[C:18]1[CH:23]=[CH:22][C:21]([N:24]2[CH2:28][C@H:27]([CH2:29][C:30](=[O:34])[C:31]([NH2:33])=[O:32])[O:26][CH2:25]2)=[CH:20][C:19]=1[F:35]>>[C:1]([CH2:3][C:4]1[N:5]=[C:6]([C:9]2[CH:14]=[CH:13][C:12]([C:18]3[CH:23]=[CH:22][C:21]([N:24]4[CH2:28][C@H:27]([CH2:29][C:30](=[O:34])[C:31]([NH2:33])=[O:32])[O:26][CH2:25]4)=[CH:20][C:19]=3[F:35])=[CH:11][CH:10]=2)[S:7][CH:8]=1)#[N:2]

Participants

3

Reactant 2

HCID 57471690HCID 57471690, compoundHCID 86613473HCID 86613473, compound

Product 1

HCID 86613477HCID 86613477, compound

Procedure

The same procedure as in Example 1 was conducted, except for adding 4-(4-cyanomethyl thiazol-2-yl)-bromobenzene and using (S)-3-(4-trimethylstannyl-3-fluorophenyl)-2-oxo-5-oxazolidinylmethyl acetamide as a starting material, to obtain the title compound.

Sources & evidence

ORD record
ord-11b86d58b6b246a88536efb2fcd336e4
Source dataset
uspto-grants-2015_10
Patent number
US09163043B2

Reaction notes

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