HCID 90093100, compound → N-{5-[7-Fluoro-1-(2-hydroxy-1,1-dimethyl-ethyl)-1H-pyrrolo[3,2-c]pyridine-3-carbonyl]-pyridin-3-yl}-2-(4-trifluoromethyl-pyrazol-1-yl)-acetamide

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Reaction Steps

To a solution of N-(5-{1-[2-(tert-Butyl-dimethyl-silanyloxy)-1,1-dimethyl-ethyl]-7-fluoro-1H-pyrrolo[3,2-c]pyridine-3-carbonyl}-pyridin-3-yl)-2-(4-trifluoromethyl-pyrazol-1-yl)-acetamide (Preparation 4, 35 mg, 56 μmol) in THF (2 mL) 4M dioxane-HCl (0.5 mL) was added and stirred at room temperature for 18 hours. The reaction was evaporated in vacuo and triturated with pentane-ether to afford the title compound as an off white solid in 100% yield, 28.54 mg.

Provenance & Evidence