HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(4-(trifluoromethyl)-1H-1,2,3-triazol-1-yl)acetic acid → HCID 90093460, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(4-(trifluoromethyl)-1H-1,2,3-triazol-1-yl)acetic acid | HCID 86672071 | — |
| Reactant | (4-aminopyridin-2-yl)[1-(2-{[tert-butyl(dimethyl)silyl]oxy}-1,1-dimethylethyl)-1H-pyrrolo[3,2-c]pyridin-3-yl]methanone | HCID 90093653 | — |
| Product | HCID 90093460 | HCID 90093460 | — |
Reaction Steps
Prepared according to the method described for Method M (Example 206) using (4-aminopyridin-2-yl)[1-(2-{[tert-butyl(dimethyl)silyl]oxy}-1,1-dimethylethyl)-1H-pyrrolo[3,2-c]pyridin-3-yl]methanone (Preparation 27) and [4-(Trifluoromethyl)-1H-1,2,3-triazol-1-yl]acetic acid (Preparation 90). The residue was purified using alumina eluting with 3% MeOH in DCM to afford the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09163021B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-9adafec622e54a9fbdbeecf53f3aefea |
| Source note | uspto-grants-2015_10 |