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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1753029Generated: October 27, 2026

2-(4-(trifluoromethyl)-1H-1,2,3-triazol-1-yl)acetic acid → HCID 90093460, compound

https://huagongshe.com/reaction/1753029

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(4-(trifluoromethyl)-1H-1,2,3-triazol-1-yl)acetic acidHCID 86672071—
Reactant(4-aminopyridin-2-yl)[1-(2-{[tert-butyl(dimethyl)silyl]oxy}-1,1-dimethylethyl)-1H-pyrrolo[3,2-c]pyridin-3-yl]methanoneHCID 90093653—
ProductHCID 90093460HCID 90093460—

Reaction Steps

Prepared according to the method described for Method M (Example 206) using (4-aminopyridin-2-yl)[1-(2-{[tert-butyl(dimethyl)silyl]oxy}-1,1-dimethylethyl)-1H-pyrrolo[3,2-c]pyridin-3-yl]methanone (Preparation 27) and [4-(Trifluoromethyl)-1H-1,2,3-triazol-1-yl]acetic acid (Preparation 90). The residue was purified using alumina eluting with 3% MeOH in DCM to afford the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09163021B2
Source datasetuspto-grants-2015_10
ORD IDord-9adafec622e54a9fbdbeecf53f3aefea
Source noteuspto-grants-2015_10