4-Cyanophenylacetic acid → N-(5-{[1-(2-{[tert-butyl(dimethyl)silyl]oxy}-1,1-dimethylethyl)-1H-pyrrolo[3,2-c]pyridin-3-yl]carbonyl}pyridin-3-yl)-2-(4-cyanophenyl)acetamide

Participants

Role	Name	HCID	Charge
Reactant	4-Cyanophenylacetic acid	HCID 79587	—
Reactant	(5-aminopyridin-3-yl)[1-(2-{[tert-butyl(dimethyl)silyl]oxy}-1,1-dimethylethyl)-1H-pyrrolo[3,2-c]pyridin-3-yl]methanone	HCID 90093072	—
Product	N-(5-{[1-(2-{[tert-butyl(dimethyl)silyl]oxy}-1,1-dimethylethyl)-1H-pyrrolo[3,2-c]pyridin-3-yl]carbonyl}pyridin-3-yl)-2-(4-cyanophenyl)acetamide	HCID 90093661	—

Reaction Steps

Prepared according to Method Z (Preparation 8) using (5-Amino-pyridin-3-yl)-{1-[2-(tert-butyl-dimethyl-silanyloxy)-1,1-dimethyl-ethyl]-1H-pyrrolo[3,2-c]pyridin-3-yl}-methanone (Preparation TT) and 4-cyanophenylacetic acid.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US09163021B2
Source dataset	uspto-grants-2015_10
ORD ID	ord-db65e6f8569740d0aeccde3729a7c5a2
Source note	uspto-grants-2015_10