5-((Diphenylmethylene)amino)-N-methoxy-N-methylnicotinamide → HCID 90093878, compound
Reaction equation
Br[C:2]1[C:6]2[CH:7]=[N:8][CH:9]=[C:10]([F:11])[C:5]=2[N:4]([CH:12]([CH3:14])[CH3:13])[CH:3]=1.[C:15]1([C:21](=[N:28][C:29]2[CH:30]=[N:31][CH:32]=[C:33]([CH:40]=2)[C:34](N(OC)C)=[O:35])[C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>>[C:15]1([C:21](=[N:28][C:29]2[CH:40]=[C:33]([C:34]([C:2]3[C:6]4[CH:7]=[N:8][CH:9]=[C:10]([F:11])[C:5]=4[N:4]([CH:12]([CH3:14])[CH3:13])[CH:3]=3)=[O:35])[CH:32]=[N:31][CH:30]=2)[C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1Participants
3
Procedure
Prepared according to the method described for Preparation 36 using 3-bromo-7-fluoro-1-isopropyl-1H-pyrrolo[3,2-c]pyridine (Preparation 46) and 5-[(diphenylmethylene)amino]-N-methoxy-N-methylnicotinamide (Preparation 52). Taken on directly to the next step.
Workup
- customPrepared
Sources & evidence
- ORD record
- ord-a004c3edde9d42ddb338761e90111878
- Source dataset
- uspto-grants-2015_10
- Patent number
- US09163021B2
Reaction notes
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