2-Bromo-N-methoxy-N-methylisonicotinamide → HCID 90093825, compound

HRID 1753050Notes

Reaction equation

HRID 1753050 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]([CH:11]=[CH:12][N:13]=1)[C:5](N(OC)C)=[O:6].I[C:15]1[C:19]2[CH:20]=[N:21][CH:22]=[CH:23][C:18]=2[N:17]([CH2:24][CH2:25][O:26][CH:27]2[CH2:32][CH2:31][CH2:30][CH2:29][O:28]2)[CH:16]=1>>[Br:1][C:2]1[CH:3]=[C:4]([C:5]([C:15]2[C:19]3[CH:20]=[N:21][CH:22]=[CH:23][C:18]=3[N:17]([CH2:24][CH2:25][O:26][CH:27]3[CH2:32][CH2:31][CH2:30][CH2:29][O:28]3)[CH:16]=2)=[O:6])[CH:11]=[CH:12][N:13]=1

Participants

3

Reactant 2

HCID 448186542-Bromo-N-methoxy-N-methylisonicotinamideHCID 118341239HCID 118341239, compound

Product 1

HCID 90093825HCID 90093825, compound

Procedure

Prepared according to the method described for Preparation 37 using 2-bromo-N-methoxy-N-methylisonicotinamide and 3-iodo-1-[2-(tetrahydro-2H-pyran-2-yloxy)ethyl]-1H-pyrrolo[3,2-c]pyridine (Preparation 50).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-a6ab997d19f041869d089b795a0216fb
Source dataset
uspto-grants-2015_10
Patent number
US09163021B2

Reaction notes

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