tert-Butyl bromoacetate → HCID 70847644, compound

HRID 1753077Notes

Reaction equation

HRID 1753077 reaction equation
[F:1][C:2]([F:9])([F:8])[C:3]1[CH:4]=[N:5][NH:6][CH:7]=1.Br[CH2:11][C:12]([O:14][C:15]([CH3:18])([CH3:17])[CH3:16])=[O:13]>>[C:15]([O:14][C:12](=[O:13])[CH2:11][N:5]1[CH:4]=[C:3]([C:2]([F:9])([F:8])[F:1])[CH:7]=[N:6]1)([CH3:18])([CH3:17])[CH3:16]

Participants

3

Reactant 2

HCID 79177tert-Butyl bromoacetateHCID 127777954-(Trifluoromethyl)-1H-pyrazole

Product 1

HCID 70847644HCID 70847644, compoundYield 24%

Procedure

The title compound was prepared according to the method described for Preparation 75 using 4-(trifluoromethyl)-1H-pyrazole and tert butyl bromoacetate to afford the title compound as a yellow solid (24%, 1.32 g).

Workup

  1. customThe title compound was prepared

Sources & evidence

ORD record
ord-6cee82ff57e041e681991a26604b1101
Source dataset
uspto-grants-2015_10
Patent number
US09163021B2

Reaction notes

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