Ethyl bromoacetate → HCID 59321669, compound

HRID 1753113Notes

Reaction equation

HRID 1753113 reaction equation
[CH:1]([C:4]1[CH:8]=[CH:7][NH:6][N:5]=1)([CH3:3])[CH3:2].Br[CH2:10][C:11]([O:13]CC)=[O:12]>>[CH:1]([C:4]1[CH:8]=[CH:7][N:6]([CH2:10][C:11]([OH:13])=[O:12])[N:5]=1)([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 7748Ethyl bromoacetateHCID 178439403HCID 178439403, compound

Product 1

HCID 59321669HCID 59321669, compound

Procedure

Prepared according to the analogous method described for Preparation 75, using 3-isopropyl-1H-pyrazole and ethyl bromoacetate isolating the higher running peak as the desired isomer, followed by the hydrolysis method of Preparation 74.

Workup

  1. customPrepared
  2. customdescribed for Preparation 75
  3. customfollowed by the hydrolysis method of Preparation 74

Sources & evidence

ORD record
ord-64569a7d766444c1b7d540c2b24d381c
Source dataset
uspto-grants-2015_10
Patent number
US09163021B2

Reaction notes

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