HCID 117818873, compound → HCID 117818947, compound

Participants

Reaction Steps

To a solution of 1-((6-methoxy-5-methylpyrimidin-4-yl)methyl)-3-nitro-1H-pyrrolo[3,2-b]pyridine (0.15 g, 0.58 mmol) in ethanol (5 mL) was added Pd/C (0.03 g). The reaction mixture was hydrogenated under balloon pressure for 16 h at RT. The solvent was filtered and evaporated under the reduced pressure to yield 1-((6-methoxy-5-methylpyrimidin-4-yl)methyl)-1H-pyrrolo[3,2-b]pyridin-3-amine (25d) 0.1 g (74%).

Provenance & Evidence