HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Sulfate → Methyl 4-amino-o-anisate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Sulfate | HCID 24436 | — |
| Reactant | Methyl 2-methoxy-4-nitrobenzoate | HCID 10798535 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Methyl 4-amino-o-anisate | HCID 168705 | 100.3% |
Reaction Steps
The hydrogenation of methyl 2-methoxy-4-nitrobenzoate (700 mg, 3.3 mmol) in methanol (10 mL) catalyzed by 5% Pd—C (100 mg) and Na2SO4 (100 mg) at 50 psi for 1 h gave methyl 4-amino-2-methoxybenzoate (600 mg, quant.) as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09162989B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-2c9d209da9bc45f6bc6f869112ded1f7 |
| Source note | uspto-grants-2015_10 |