Sodium Chloride → HCID 67979692, compound

Participants

Reaction Conditions

Reaction Steps

ethyl thioglycolate (0.85 g, 0.77 mL, 7 mmol) was added to a mixture of 4 (4.5 g, 6.74 mmol), K2CO3 (1.86 g, 13.5 mmol), and N,N-dimethylformamide (DMF) (70 mL) at room temperature. The resulting mixture was stirred for 12 hrs at room temperature and another 12 hrs at 50° C. The mixture was then poured into an aqueous sodium chloride solution (100 mL) and extracted with ethyl acetate (150 mL). The organic layer was separated, washed with saturated aqueous sodium chloride solution (4×150 mL), and dried over MgSO4. The crude product was obtained after evaporating off the solvent and used in the next step without further purification (4.2 g, 91% yield).

Provenance & Evidence