Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dibutylamine | HCID 8148 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | (+-)-Tetrahydro-2-furoic acid | HCID 86079 | — |
| Reactant | HCID 21974002 | HCID 21974002 | — |
| Reactant | HCID 178527019 | HCID 178527019 | — |
| Product | HCID 3414196 | HCID 3414196 | — |
Reaction Steps
232 g (2 mols) of 2-tetrahydrofuroic acid, 387 g (3 mols) of dibutyl amine and 1,5 g of sodium hypophosphite, were introduced into a stirred reactor at room temperature. Reaction mixture was gradually heated up to 200° C., separating the reaction water and returning the excess of dibutyl amine into the reactor. Reaction was controlled by its acid value. Once the acid value was lower than 10 mg KOH/g, excess of dibutyl amide was distilled at 60-100° C. under vacuum.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US09167812B2 |
|---|
| Source dataset | uspto-grants-2015_10 |
|---|
| ORD ID | ord-af014575523a4053bdba73f957c78d9d |
|---|
| Source note | uspto-grants-2015_10 |
|---|
