Cyclohexane, (bromomethyl)- → HCID 54766585, compound

HRID 1753754Notes

Reaction equation

HRID 1753754 reaction equation
[CH3:1][C:2]1[C:14]2[NH:13][C:12]3[C:7](=[CH:8][CH:9]=[C:10]([OH:15])[CH:11]=3)[C:6]=2[CH:5]=[CH:4][N:3]=1.Br[CH2:17][CH:18]1[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]1>>[CH3:1][C:2]1[C:14]2[N:13]([CH2:17][CH:18]3[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]3)[C:12]3[C:7](=[CH:8][CH:9]=[C:10]([O:15][CH2:6][CH:7]4[CH2:12][CH2:11][CH2:10][CH2:9][CH2:8]4)[CH:11]=3)[C:6]=2[CH:5]=[CH:4][N:3]=1

Participants

3

Reactant 2

HCID 137636Cyclohexane, (bromomethyl)-HCID 178432657HCID 178432657, compound

Product 1

HCID 54766585HCID 54766585, compoundYield 75%

Procedure

The title compound was synthesized from 1-methyl-7-hydroxy-β-carboline (0.5 g, 1.587 mmol) in presence of 1-bromomethylcyclohexane (1.240 g, 3.173 mmol) as described here above.

Sources & evidence

ORD record
ord-2820ec199cc6448c9ba76796df1d9bb3
Source dataset
uspto-grants-2015_10
Patent number
US09168247B2

Reaction notes

Loading…