Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Pyrrolidinopyridine → 4-Hydrazino-6-(4-pyrrolidin-1-ylpiperidin-1-yl)pyrimidine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Pyrrolidinopyridine | HCID 75567 | — |
| 반응물 | 4-Chloro-6-hydrazinylpyrimidine | HCID 247222 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 4-Hydrazino-6-(4-pyrrolidin-1-ylpiperidin-1-yl)pyrimidine | HCID 59603700 | — |
반응 단계
A mixture of 2.0 g (13.8 mmol) of the compound from Example 7A and 4.3 g (27.7 mmol) 4-pyrrolidin-1-ylpyridine is stirred in 20 ml water at 100° C. for 16 h. The solid which has precipitated out is filtered off, washed first with ethanol and then with diethyl ether and dried in vacuo.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09168249B2 |
| 출처 데이터셋 | uspto-grants-2015_10 |
| ORD ID | ord-a5d3caab4cc24a7aae1f6c16ab355b33 |
| 출처 메모 | uspto-grants-2015_10 |