Dimethylformamide diethylacetal → HCID 67456926, compound

HRID 1753814Notes

Reaction equation

HRID 1753814 reaction equation
[CH2:1]([O:3][C:4](=[O:11])[CH2:5][N:6]1[CH:10]=[N:9][CH:8]=[N:7]1)[CH3:2].C(O[CH:15](OCC)[N:16]([CH3:18])[CH3:17])C>>[CH2:1]([O:3][C:4](=[O:11])[C:5]([N:6]1[CH:10]=[N:9][CH:8]=[N:7]1)=[CH:15][N:16]([CH3:18])[CH3:17])[CH3:2]

Participants

3

Reactant 2

HCID 70913Dimethylformamide diethylacetalHCID 557521Ethyl 1H-1,2,4-triazole-1-acetate

Product 1

HCID 67456926HCID 67456926, compound

Procedure

1.9 g (9.8 mmol) [1,2,4]-triazol-1-ylacetic acid ethyl ester [Ainsworth et al., J. Am. Chem. Soc. 1955, 77, 621-623] and 3.6 ml (2.9 g, 19.6 mmol) dimethylformamide diethyl acetal are stirred at a bath temperature of 100° C. for 12 h. For working up, the cooled reaction solution is concentrated on a rotary evaporator and the residue is dried in vacuo.

Workup

  1. customthe cooled reaction solution
  2. concentrationis concentrated on a rotary evaporator
  3. customthe residue is dried in vacuo

Sources & evidence

ORD record
ord-ebb8aab835264addaee515aecbdb939f
Source dataset
uspto-grants-2015_10
Patent number
US09168249B2

Reaction notes

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