1,4-Dioxa-8-azaspiro(4.5)decane → HCID 131733664, compound

HRID 1753973Notes

Reaction equation

HRID 1753973 reaction equation
[CH2:1]([O:3][C:4](=[O:17])[CH2:5][N:6]1[N:10]=[N:9][C:8]([C:11]2[S:15][C:14](Br)=[N:13][CH:12]=2)=[N:7]1)[CH3:2].[O:18]1[C:22]2([CH2:27][CH2:26][NH:25][CH2:24][CH2:23]2)[O:21][CH2:20][CH2:19]1>>[CH2:1]([O:3][C:4](=[O:17])[CH2:5][N:6]1[N:10]=[N:9][C:8]([C:11]2[S:15][C:14]([N:25]3[CH2:26][CH2:27][C:22]4([O:21][CH2:20][CH2:19][O:18]4)[CH2:23][CH2:24]3)=[N:13][CH:12]=2)=[N:7]1)[CH3:2]

Participants

3

Reactant 2

HCID 674351,4-Dioxa-8-azaspiro(4.5)decaneHCID 58042988HCID 58042988, compound

Product 1

HCID 131733664HCID 131733664, compound

Procedure

The title compound was prepared in a similar manner as that described for Example 13 (step 1) from Intermediate 2 and 1,4-dioxa-8-azaspiro[4.5]decane.

Sources & evidence

ORD record
ord-6434b6b8b2e7458794e5eb81aeb391c2
Source dataset
uspto-grants-2015_10
Patent number
US09168248B2

Reaction notes

Loading…