Hydrogen Bromide → HCID 86720214, compound

Participants

Reaction Steps

The above-described method (Example 1) was repeated to react hexyl 2-amino-3-methylbenzoate (2.50 g, 10 mmol) with hydrogen bromide (2.21 g, 13 1 mmol, 48% in water) and hydrogen peroxide (1.72 g, 15.0 mmol, 30% in water). Following working up similar to Example 1 and additional column chromatography, hexyl 2-amino-5-bromo-3-methylbenzoate (2.5 g, 78.8% of theory, >99 area % LC) was obtained as a brown oil.

Provenance & Evidence