Hydrogen Bromide → HCID 86720215, compound

Participants

Reaction Steps

The above-described method (Example 1) was repeated to react 2-ethylhexyl 2-amino-3-methylbenzoate (3.00 g, 10.6 mmol) with hydrogen bromide (2.33 g, 13 8 mmol, 48% in water) and hydrogen peroxide (1.81 g, 15.9 mmol, 30% in water). Following working up similar to Example 1 and additional column chromatography, 2-ethylhexyl 2-amino-5-bromo-3-methylbenzoate (2.7 g, 74.0% of theory, >99 area % LC) was obtained as a brown oil.

Provenance & Evidence