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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1754225Generated: October 27, 2026

2-(Benzyloxy)benzaldehyde → 4-(2-Benzyloxy-benzyl)-piperazine-1-carboxylic acid phenylamide

https://huagongshe.com/reaction/1754225

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Benzyloxy)benzaldehydeHCID 344784—
ReactantN-phenylpiperazine-1-carboxamideHCID 7015289—
Product4-(2-Benzyloxy-benzyl)-piperazine-1-carboxylic acid phenylamideHCID 57880873—

Reaction Steps

The title compound was prepared from piperazine-1-carboxylic acid phenylamide and 2-benzyloxybenzaldehyde. 1H NMR (400 MHz, CDCl3): 7.49-7.20 (m, 11H), 7.05-6.92 (m, 3H), 6.41 (s, 1H), 5.08 (s, 2H), 3.65 (s, 2H), 3.51-3.45 (m, 4H), 2.55-2.49 (m, 4H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09169224B2
Source datasetuspto-grants-2015_10
ORD IDord-5ab48e4da02a4026a7bcdb6d3ef3e306
Source noteuspto-grants-2015_10